2022
Tara Hicks, Shalini Trivedi*, Mikayla Eppert, Richard Bowman, Hui Tian, Amna Dafalla, Caroline Crahan, Sarit Smolikove#, Nicola Silva*#
Continuous double-strand break induction and their differential processing sustain chiasma formation during Caenorhabditis elegans meiosis
Cell Rep. 2022 Sep 27;40(13):111403. doi: 10.1016/j.celrep.2022.111403. PMID: 36170820
*Silva Lab members
# Co-corresponding
mmc2.pdfTara Hicks, Emily Koury, Caleb McCabe, Cameron Williams, Caroline Crahan, Sarit Smolikove
Nucleic Acids Res. 2022 Aug 12;50(14):8041-8059. doi: 10.1093/nar/gkac621.
PMID: 35871299
gkac621.pdf2021
RPA complexes in Caenorhabditis elegans meiosis; unique roles in replication, meiotic recombination and apoptosis.
Hefel A, Honda M*, Cronin N, Harrell K, Patel P, Spies M*, Smolikove S.
Nucleic Acids Res. 2021 Feb 26;49(4):2005-2026. doi: 10.1093/nar/gkaa1293.
PMID: 33476370 *Spies Lab Members
gkaa1293.pdfRecruitment of MRE-11 to complex DNA damage is modulated by meiosis-specific chromosome organization
Kailey Harrell, Madison Day, Sarit Smolikove
Mutat Res. Jan-Jun 2021;822:111743. doi: 10.1016/j.mrfmmm.2021.111743. Epub 2021 Apr 20.
1-s2.0-S0027510721000063-main.pdfCollaboration with the Yanowitz lab: Aging Negatively Impacts DNA Repair and Bivalent Formation in the C. elegans Germ Line
Marilina Raices*, Richard Bowman, Sarit Smolikove, Judith L Yanowitz*
Front Cell Dev Biol
. 2021 Aug 4;9:695333. doi: 10.3389/fcell.2021.695333. eCollection 2021. *Yanowitz Lab Members
fcell-09-695333.pdf2020
Akirin proteins in development and disease: critical roles and mechanisms of action.
Bosch PJ, Peek SL, Smolikove S, Weiner JA.
Cell Mol Life Sci. 2020 May 2. doi: 10.1007/s00018-020-03531-w. Online ahead of print.
PMID: 32361777 Review.
Bosch2020_Article_AkirinProteinsInDevelopmentAnd.pdfAkirin Is Required for Muscle Function and Acts Through the TGF-β
Sma/Mab Signaling Pathway in Caenorhabditis elegans Development.
Bowman R, Balukoff N, Clemons A, Koury E, Ford T, Baxi K, de Carvalho CE,
Smolikove S.
G3 (Bethesda).
2019 Nov 25. pii: g3.400377.2019. doi: 10.1534/g3.119.400377. [Epub ahead of
print] PubMed PMID: 31767636.
387.full_.pdf2019
CRL4 regulates
recombination and synaptonemal complex aggregation in the Caenorhabditis elegans
germline.
Alleva B, Clausen S, Koury E, Hefel A, Smolikove S.
PLoS Genet. 2019 Nov 18;15(11):e1008486. doi:
10.1371/journal.pgen.1008486. eCollection 2019 Nov. PubMed PMID: 31738749.
journal.pgen_.1008486.pdfTissue-Specific Split sfGFP System for Streamlined Expression of GFP Tagged Proteins in the Caenorhabditis elegans Germline. Hefel A, Smolikove S. G3 (Bethesda). 2019 Apr 16. pii: g3.400162.2019. doi: 10.1534/g3.119.400162.
PMID: 30992318
1933.pdfHarrell KE, Koury E, Smolikove S. Microirradiation for Precise, Double-strand
Break Induction in vivo in Caenorhabditis elegans. Bio Protoc. 2018 Dec 20;8(24).
pii: e3130. doi: 10.21769/BioProtoc.3130. PubMed PMID: 30680294; PubMed Central
PMCID: PMC6342474
nihms-1003918.pdf2018
Bowman R, Balukof N, Ford T, Smolikove S. 2018
A Novel Role for α-importins and Akirin in Establishment of Meiotic Sister Chromatid Cohesion in Caenorhabditis elegans.
Genetics
Bowman-et-al-2019-1.pdfReichman R, Shi Z, Malone R, Smolikove S. 2018. Mitotic and Meiotic Functions for the SUMOylation Pathway in the Caenorhabditis elegans Germline.
Genetics. 2018 Apr;208(4):1421-1441.
2018-Genetics-Reichman-et-al.pdfKoury E, Harrell K, Smolikove S. 2018. Differential RPA-1 and RAD-51 recruitment in vivo throughout the C. elegans germline, as revealed by laser microirradiation. Nucleic Acid Research.
2018-Nucleic-Acids-Res-Koury-et-al.pdf2017
Alleva B, Smolikove S. 2017. Moving and stopping: Regulation of chromosome movement to promote meiotic chromosome pairing and synapsis. Nucleus. 11:1-12. Review
2017-Nucleus-Alleva-and-Smolikove.pdfAlleva B, Balukoff N, Peiper A, Smolikove S. 2017. Regulating chromosomal movement by the cochaperone FKB-6 ensures timely pairing and synapsis. Journal of Cell Biology. 216(2):393-408
2017-JCB-Alleva-et-al.pdf2016
Yin Y, Donlevy S, Smolikove S. 2016. Coordination of Recombination with Meiotic Progression in the Caenorhabditis elegans Germline by KIN-18, a TAO Kinase That Regulates the Timing of MPK-1 Signaling. Genetics. 202(1):45-59
2016-Genetics-Yin-et-al.pdf2014
Brockway HM, Balukoff N, Dean M, Alleva B, Smolikove S. 2014. Signalosome Regulates Synaptonemal Complex Assembly during Meiotic Prophase I of Caenorhabditis elegans.. Plos Genetics. 10(11
journal.pgen_.1004757.pdf2013
Clemons AM, Brockway HM, Yin Y, Kasinathan B, Butterfield YS, Jones SJM, Colaiácovo MP, Smolikove S. 2013. akirin is required for diakinesis bivalent structure and synaptonemal complex disassembly at meiotic prophase I.. Mol Biol Cell. 24(7):1053-67
Clemons-et-al-2013.pdfYin Y, Smolikove S. 2013. Impaired resection of meiotic double-strand breaks channels repair to nonhomologous end joining in Caenorhabditis elegans.. Mol Cell Biol. 33(14):2732-47
2013-MCB-Yin.pdf2011
Schild-Prüfert K, Saito TT, Smolikov S, Gu Y, Hincapie M, Hill DE, Vidal M, McDonald K, Colaiácovo MP. 2011. Organization of the synaptonemal complex during meiosis in Caenorhabditis elegans.. Genetics. 189(2):411-21
SC.pdf2009
Smolikov S, Schild-Prüfert K, Colaiácovo MP. 2009. A yeast two-hybrid screen for SYP-3 interactors identifies SYP-4, a component required for synaptonemal complex assembly and chiasma formation in Caenorhabditis elegans meiosis.. PLoS Genet. 5(10):e1000669.
SYP-4.pdf2008
Smolikov S, Schild-Prüfert K, Colaiácovo MP. 2008. CRA-1 uncovers a double-strand break-dependent pathway promoting the assembly of central region proteins on chromosome axes during C. elegans meiosis.. PLoS Genet. 4(6):e1000088
CRA-1.pdfde Carvalho C E, Zaaijer S, Smolikov S, Gu Y, Schumacher JM, Colaiácovo MP. 2008. LAB-1 antagonizes the Aurora B kinase in C. elegans.. Genes Dev. 22(20):2869-85.
LAB-1.pdf2007
Smolikov S, Eizinger A, Hurlburt A, Rogers E, Villeneuve AM, Colaiácovo MP. 2007. Synapsis-defective mutants reveal a correlation between chromosome conformation and the mode of double-strand break repair during Caenorhabditis elegans meiosis.. Genetics. 176(4):2027-33.
SYP-3-recombination.pdfSmolikov S, Eizinger A, Schild-Prüfert K, Hurlburt A, McDonald K, Engebrecht JA, Villeneuve AM, Colaiácovo MP. 2007. SYP-3 restricts synaptonemal complex assembly to bridge paired chromosome axes during meiosis in Caenorhabditis elegans.. Genetics. 176(4):2015-25.
SYP-3-synapsis.pdf2006
Whetstine JR, Nottke A, Lan F, Huarte M, Smolikov S, Chen Z, Spooner E, Li E, Zhang G, Colaiacovo M et al.. 2006. Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases.. Cell. 125(3):467-81.
JMJD2A.pdf
