Publications - Smolikove Lab - The University of Iowa

2024

Temporal Analysis of DSB Repair Outcome in Caenorhabditis elegans Meiosis. Hicks T, Silva N, Smolikove S. Methods Mol Biol. 2024;2818:195-212. doi: 10.1007/978-1-0716-3906-1_13. PMID: 39126476

2022

Tara Hicks, Shalini Trivedi, Mikayla Eppert, Richard Bowman, Hui Tian, Amna Dafalla, Caroline Crahan, Sarit Smolikove#, Nicola Silva# Continuous double-strand break induction and their differential processing sustain chiasma formation during Caenorhabditis elegans meiosis Cell Rep. 2022 Sep 27;40(13):111403. doi: 10.1016/j.celrep.2022.111403. PMID: 36170820 *Silva Lab members # Co-corresponding

Tara Hicks, Emily Koury, Caleb McCabe, Cameron Williams, Caroline Crahan, Sarit Smolikove Nucleic Acids Res. 2022 Aug 12;50(14):8041-8059. doi: 10.1093/nar/gkac621. PMID: 35871299

ATM/ATR kinases link the synaptonemal complex and DNA double-strand break repair pathway choice. Láscarez-Lagunas LI, Nadarajan S, Martinez-Garcia M, Quinn JN, Todisco E, Thakkar T, Berson E, Eaford D, Crawley O, Montoya A, Faull P, Ferrandiz N, Barroso C, Labella S, Koury E, Smolikove S, Zetka M, Martinez-Perez E, Colaiácovo MP. Curr Biol. 2022 Nov 7;32(21):4719-4726.e4. doi: 10.1016/j.cub.2022.08.081. Epub 2022 Sep 21. PMID: 36137547

2021

RPA complexes in Caenorhabditis elegans meiosis; unique roles in replication, meiotic recombination and apoptosis. Hefel A, Honda M, Cronin N, Harrell K, Patel P, Spies M, Smolikove S. Nucleic Acids Res. 2021 Feb 26;49(4):2005-2026. doi: 10.1093/nar/gkaa1293. PMID: 33476370 *Spies Lab Members

Recruitment of MRE-11 to complex DNA damage is modulated by meiosis-specific chromosome organization Kailey Harrell, Madison Day, Sarit Smolikove Mutat Res. Jan-Jun 2021;822:111743. doi: 10.1016/j.mrfmmm.2021.111743. Epub 2021 Apr 20.

1-s2.0-S0027510721000063-main.pdf

Collaboration with the Yanowitz lab: Aging Negatively Impacts DNA Repair and Bivalent Formation in the C. elegans Germ Line Marilina Raices, Richard Bowman, Sarit Smolikove, Judith L Yanowitz Front Cell Dev Biol . 2021 Aug 4;9:695333. doi: 10.3389/fcell.2021.695333. eCollection 2021. *Yanowitz Lab Members

fcell-09-695333.pdf

2020

Akirin proteins in development and disease: critical roles and mechanisms of action. Bosch PJ, Peek SL, Smolikove S, Weiner JA. Cell Mol Life Sci. 2020 May 2. doi: 10.1007/s00018-020-03531-w. Online ahead of print. PMID: 32361777 Review.

Bosch2020_Article_AkirinProteinsInDevelopmentAnd.pdf

Akirin Is Required for Muscle Function and Acts Through the TGF-β Sma/Mab Signaling Pathway in Caenorhabditis elegans Development. Bowman R, Balukoff N, Clemons A, Koury E, Ford T, Baxi K, de Carvalho CE, Smolikove S. G3 (Bethesda). 2019 Nov 25. pii: g3.400377.2019. doi: 10.1534/g3.119.400377. [Epub ahead of print] PubMed PMID: 31767636.

2019

CRL4 regulates recombination and synaptonemal complex aggregation in the Caenorhabditis elegans germline. Alleva B, Clausen S, Koury E, Hefel A, Smolikove S. PLoS Genet. 2019 Nov 18;15(11):e1008486. doi: 10.1371/journal.pgen.1008486. eCollection 2019 Nov. PubMed PMID: 31738749.

journal.pgen_.1008486.pdf

Tissue-Specific Split sfGFP System for Streamlined Expression of GFP Tagged Proteins in the Caenorhabditis elegans Germline. Hefel A, Smolikove S. G3 (Bethesda). 2019 Apr 16. pii: g3.400162.2019. doi: 10.1534/g3.119.400162. PMID: 30992318

Harrell KE, Koury E, Smolikove S. Microirradiation for Precise, Double-strand Break Induction in vivo in Caenorhabditis elegans. Bio Protoc. 2018 Dec 20;8(24). pii: e3130. doi: 10.21769/BioProtoc.3130. PubMed PMID: 30680294; PubMed Central PMCID: PMC6342474

nihms-1003918.pdf

2018

Bowman R, Balukof N, Ford T, Smolikove S. 2018 A Novel Role for α-importins and Akirin in Establishment of Meiotic Sister Chromatid Cohesion in Caenorhabditis elegans. Genetics

Bowman-et-al-2019-1.pdf

Reichman R, Shi Z, Malone R, Smolikove S. 2018. Mitotic and Meiotic Functions for the SUMOylation Pathway in the Caenorhabditis elegans Germline. Genetics. 2018 Apr;208(4):1421-1441.

2018-Genetics-Reichman-et-al.pdf

Koury E, Harrell K, Smolikove S. 2018. Differential RPA-1 and RAD-51 recruitment in vivo throughout the C. elegans germline, as revealed by laser microirradiation. Nucleic Acid Research.

2018-Nucleic-Acids-Res-Koury-et-al.pdf

2017

Alleva B, Smolikove S. 2017. Moving and stopping: Regulation of chromosome movement to promote meiotic chromosome pairing and synapsis. Nucleus. 11:1-12. Review

2017-Nucleus-Alleva-and-Smolikove.pdf

Reichman R, Alleva B, Smolikove S. 2017. Prophase I: Preparing Chromosomes for Segregation in the Developing Oocyte. Results Probl Cell Differ. 59:125-173. Review

2017-Results-Probl-Cell-Differ-Alleva-and-Smolikove.pdf

Alleva B, Balukoff N, Peiper A, Smolikove S. 2017. Regulating chromosomal movement by the cochaperone FKB-6 ensures timely pairing and synapsis. Journal of Cell Biology. 216(2):393-408

2017-JCB-Alleva-et-al.pdf

2016

Yin Y, Donlevy S, Smolikove S. 2016. Coordination of Recombination with Meiotic Progression in the Caenorhabditis elegans Germline by KIN-18, a TAO Kinase That Regulates the Timing of MPK-1 Signaling. Genetics. 202(1):45-59

2016-Genetics-Yin-et-al.pdf

2014

Brockway HM, Balukoff N, Dean M, Alleva B, Smolikove S. 2014. Signalosome Regulates Synaptonemal Complex Assembly during Meiotic Prophase I of Caenorhabditis elegans.. Plos Genetics. 10(11

journal.pgen_.1004757.pdf

2013

Clemons AM, Brockway HM, Yin Y, Kasinathan B, Butterfield YS, Jones SJM, Colaiácovo MP, Smolikove S. 2013. akirin is required for diakinesis bivalent structure and synaptonemal complex disassembly at meiotic prophase I.. Mol Biol Cell. 24(7):1053-67

Clemons-et-al-2013.pdf

Yin Y, Smolikove S. 2013. Impaired resection of meiotic double-strand breaks channels repair to nonhomologous end joining in Caenorhabditis elegans.. Mol Cell Biol. 33(14):2732-47

2013-MCB-Yin.pdf

2011

Schild-Prüfert K, Saito TT, Smolikov S, Gu Y, Hincapie M, Hill DE, Vidal M, McDonald K, Colaiácovo MP. 2011. Organization of the synaptonemal complex during meiosis in Caenorhabditis elegans.. Genetics. 189(2):411-21

2009

Smolikov S, Schild-Prüfert K, Colaiácovo MP. 2009. A yeast two-hybrid screen for SYP-3 interactors identifies SYP-4, a component required for synaptonemal complex assembly and chiasma formation in Caenorhabditis elegans meiosis.. PLoS Genet. 5(10):e1000669.

2008

Smolikov S, Schild-Prüfert K, Colaiácovo MP. 2008. CRA-1 uncovers a double-strand break-dependent pathway promoting the assembly of central region proteins on chromosome axes during C. elegans meiosis.. PLoS Genet. 4(6):e1000088

de Carvalho C E, Zaaijer S, Smolikov S, Gu Y, Schumacher JM, Colaiácovo MP. 2008. LAB-1 antagonizes the Aurora B kinase in C. elegans.. Genes Dev. 22(20):2869-85.

2007

Smolikov S, Eizinger A, Hurlburt A, Rogers E, Villeneuve AM, Colaiácovo MP. 2007. Synapsis-defective mutants reveal a correlation between chromosome conformation and the mode of double-strand break repair during Caenorhabditis elegans meiosis.. Genetics. 176(4):2027-33.

SYP-3-recombination.pdf

Smolikov S, Eizinger A, Schild-Prüfert K, Hurlburt A, McDonald K, Engebrecht JA, Villeneuve AM, Colaiácovo MP. 2007. SYP-3 restricts synaptonemal complex assembly to bridge paired chromosome axes during meiosis in Caenorhabditis elegans.. Genetics. 176(4):2015-25.

SYP-3-synapsis.pdf

2006

Whetstine JR, Nottke A, Lan F, Huarte M, Smolikov S, Chen Z, Spooner E, Li E, Zhang G, Colaiacovo M et al.. 2006. Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases.. Cell. 125(3):467-81.